December 8, 2023

Researchers on the College of Würzburg in Germany have developed a conveyable scanner that’s the first to have the ability to picture people utilizing Magnetic Particle Imaging (MPI). The expertise may present a radiation-free different to methods comparable to X-ray fluoroscopy and digital subtraction angiography for minimally invasive endovascular procedures, and is nicely fitted to viewing processes comparable to blood circulation. Earlier inceptions of MPI expertise had been too giant and costly and had been primarily designed to be used in experimental animals. That is the primary model of the expertise that’s sufficiently small for portability and it has been designed for human sufferers. The process entails administering magnetic nanoparticles to the affected person, after which the scanner measures adjustments of their response to a magnetic area over time to visualise inner processes within the physique.

Medical imaging has reworked how clinicians can examine the interior working of our our bodies, and is a mainstay of medical diagnostics. Nevertheless, that doesn’t imply that it may possibly’t be improved and up to date. A serious limitation of many imaging modalities is their use of ionizing radiation, which might trigger well being dangers for sufferers and healthcare workers alike. Creating radiation-free imaging programs is a noble objective.

“As with positron emission tomography, which depends on the administration of radioactive substances as markers, this methodology has the good benefit of being delicate and quick with out ‘seeing’ interfering background alerts from tissue or bone,” stated Volker Behr, a researcher concerned within the research.

This newest imaging modality shouldn’t be new, having been trialed in experimental animals beforehand, however that is the primary time that researchers have created an MPI imager that’s particularly for human sufferers, and which is small and light-weight sufficient to be comparatively simply moveable. The system entails utilizing magnetic nanoparticles as a tracer throughout the physique that may have an effect on magnetic fields, offering a measurable sign that reveals dynamic processes throughout the physique, comparable to blood circulation.

“On this course of, the magnetisation of nanoparticles is particularly manipulated with the assistance of exterior magnetic fields, whereby not solely their presence but additionally their spatial place within the human physique may be detected,” stated Patrick Vogel, one other researcher concerned within the research.   

Examine in journal Scientific Reviews: iMPI: portable human-sized magnetic particle imaging scanner for real-time endovascular interventions

Through: University of Würzburg